NOVEL APPLICATION OF MIXED HYDROTROPIC SOLUBILIZATION TECHNIQUE IN THE FORMULATION AND EVALUATION OF SOLID DISPERSION OF FLUPIRTINE MALEATE

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formulation and evaluation of aceclofenac injection made by mixed hydrotropic solubilization technique

aceclofenac is a non-steroidal anti-inflammatory drug (nsaid) that exhibits analgesic, antipyretic and anti-inflammatory activities. it is practically insoluble in water. the effect of hydrotropes such as urea and sodium citrate and blends (urea + sodium citrate) on the solubility of aceclofenac was investigated. the enhancement in the solubility of aceclofenac was more than 5 and 25 folds in 3...

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Formulation and Evaluation of Aceclofenac Injection Made by Mixed Hydrotropic Solubilization Technique

Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) that exhibits analgesic, antipyretic and anti-inflammatory activities. It is practically insoluble in water. The effect of hydrotropes such as urea and sodium citrate and blends (urea + sodium citrate) on the solubility of aceclofenac was investigated. The enhancement in the solubility of aceclofenac was more than 5 and 25 folds in 3...

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ژورنال

عنوان ژورنال: Journal of Drug Delivery and Therapeutics

سال: 2018

ISSN: 2250-1177

DOI: 10.22270/jddt.v8i5.1911